Bio 2012 panel on “Comparative Effectiveness” : The push for proven treatments

  1. tinkerrr
    Great tweets #bio2012 Session on Comparative Effectiveness Research: @ChristianeTrue, retweets here
    Sat, Jun 23 2012 11:02:46
  2. From the programs: The new era of Comparative Effectiveness Research (CER) raises a number of critical questions for health care, among them: What are the best strategies for disseminating CER findings to providers and patients? How will new findings help patients make informed decisions? Will new comparative studies shed more light on the diverse needs of patient subpopulations, or will they limit patient access to personalized treatments? Discuss these questions and more during this sessions.
  3. Martin Zagari,Vice President, Global Health Economics Amgen
  4. tinkerrr
    RT @ChristianeTrue: Zagari: in US, seems to be national aversion to evidence. Guidances have not been greeted warmly. #BIO2012
    Sat, Jun 23 2012 11:02:46
  5. tinkerrr
    RT @ChristianeTrue: Zagari: US has all these cultural elements that inhibit the rational, rapid dissemination of evidence. #BIO2012
    Sat, Jun 23 2012 11:02:46
  6. Background here from JAMA on CE “The Patient Protection and Affordable Care Act of 2010 created the Patient-Centered Outcomes Research Institute (PCORI) to fund and promote comparative clinical effectiveness research (CER) that will “assist patients, clinicians, purchasers, and policy-makers in making informed health decisions by advancing the quality and relevance of evidence concerning the manner in which diseases, disorders, and other health conditions can effectively and appropriately be prevented, diagnosed, treated, monitored, and managed through research and evidence synthesis.” Cite: Patient Protection and Affordable Care Act, Pub L No. 111-148, 124 Stat 727, §6301
  7. tinkerrr
    RT @ChristianeTrue: Zagari: example…management of …prostate cancer risks. Not a rational conversation on this topic in US. #BIO2012
    Sat, Jun 23 2012 11:02:46
  8. tinkerrr
    RT @ChristianeTrue: Zagari: but at insurance level, better level of use of CE evidence. But not being done In a consistent fashion. #BIO2012
    Sat, Jun 23 2012 11:02:46
  9. tinkerrr
    RT @ChristianeTrue: Zagari: we need to have good science..good transparency, Comp Eff data should be available for scrutiny. #BIO2012
    Sat, Jun 23 2012 11:02:46
  10. tinkerrr
    RT @ChristianeTrue: Zagari: Comp. effectiveness mpact on biotech, Amgen trying to come up with framework for response . #BIO2012
    Sat, Jun 23 2012 11:02:46
  11. tinkerrr
    RT @ChristianeTrue: Zagari: more and more, thinks industry will be locked out of CER discussions. Big cause of concern. #BIO2012
    Sat, Jun 23 2012 11:02:46
  12. tinkerrr
    RT @ChristianeTrue: Also on CER panel, Dr. Richard Lopez of Atrius Health. #BIO2012 Based in MA
    Sat, Jun 23 2012 11:02:46
  13. Disclosure: TR gets her care at Harvard Vanguard, owned by Atrius.
  14. tinkerrr
    RT @ChristianeTrue: Lopez of Atrius: provider groups, … still trying to understand what evidence is, nevermind Comp/E. #BIO2012
    Sat, Jun 23 2012 11:02:46
  15. tinkerrr
    MT @ChristianeTrue: Lopez: with guidelines)…a lot of inertia, a lot of special interest, hard to overcome. #BIO2012
    Sat, Jun 23 2012 11:02:46
  16. tinkerrr
    RT @ChristianeTrue: Lopez: ACP coming out soon with guidance on prostate screening midway between task force statement and ideal. #bio2012
    Sat, Jun 23 2012 11:02:46
  17. ChristianeTrue
    Lopez: ACOs may become better partners for carrying out randomized trials. Can also pick up signals from health group data. #BIO2012
    Sat, Jun 23 2012 11:21:11
  18. Tom HubbardSenior Program Director NEHI
  19. tinkerrr
    MT @ChristianeTrue: Hubbard: … no. of players in Comp. effect. has grown, including big integrated HC systems w/lots of data. #BIO2012
    Sat, Jun 23 2012 11:02:46
  20. Sarah K. Emond CEO, Institute for Clinical and Economic Review
  21. tinkerrr
    RT @ChristianeTrue: Emond: PCORI can take some of the heat for us, but will not be setting cost/value issues. #BIO2012 http://www.pcori.org/
    Sat, Jun 23 2012 11:02:46
  22. tinkerrr
    RT @ChristianeTrue: Emond: a lot of this comes back to how misaligned the financial incentives are in our HC system. #BIO2012
    Sat, Jun 23 2012 11:02:46
  23. ChristianeTrue
    Emond: will win if have system that supports doc’s judgment in use of comparative effectiveness research. #BIO2012
    Fri, Jun 22 2012 04:58:05
  24. tinkerrr
    RT @ChristianeTrue: Hubbard to Zagari: Will ACOs turn down new drugs? Zagari: will have to have overwhelming benefits evidence. #BIO2012
    Sat, Jun 23 2012 11:02:46
  25. tinkerrr
    MT @ChristianeTrue: Zagari: (on how biotechs get in on CE discussion) work with institutions such as Kaiser that have research arm. #BIO2012
    Sat, Jun 23 2012 11:02:46
  26. tinkerrr
    RT @ChristianeTrue: Zagari: have keep ini mind all this data fraught with bias (… that’s what makes claims data hard to use. #BIO2012
    Sat, Jun 23 2012 11:02:46
  27. ChristianeTrue
    Zagari: heterogeneity vastly understudied, few studies look at drug to drug. If you give a drug and not working, can stop faster. #BIO2012
    Sat, Jun 23 2012 11:10:10
  28. ChristianeTrue
    Zagari: (on how biotechs can not be locked out of CE discussion) work with institutions such as Kaiser that have research arm. #BIO2012
    Sat, Jun 23 2012 11:19:28
  29. tinkerrr
    RT @ChristianeTrue: Zagari: sees partnerships around data, encouraging physicians to collect data,…have a national clearinghouse. #BIO2012
    Sat, Jun 23 2012 11:02:46
  30. ChristianeTrue
    Lopez: guidelines are not about saying you have to apply to every patient, but getting providers to think about how care provided. #BIO2012
    Sat, Jun 23 2012 11:10:10
  31. ChristianeTrue
    Lopez: saying medicine is an art shouldn’t mean I am just going to do what feels good. #BIO2012
    Sat, Jun 23 2012 11:10:10
  32. And later in the week, BU held a session on …

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: